Any way to run multiple instances of the same excel workbook with macros?

I have a large macro enabled workbook that processes data and exports it in a usable format. some of the data that it processes can be large and take a while to run through the workbook. I'd like to be able to open this workbook multiple times to process multiple data sets at once. is there any way that this can be done?

I am using a python 3 app that I developed to manage the books and am more than open to using other languages and software.